张珊珊博士

基本信息

姓名：张珊珊

职称：讲师

研究方向：基于计算机辅助靶向重要靶标的先导化合物发现，优化及结合机制研究

院系：食品与药学学院药学系

电子邮箱：Zhangss0824@163.com

学习/工作经历

2026.07-至今    浙江海洋大学  讲师

2022.09-2026.03  浙江理工大学  博士

2019.09-2022.06  浙江海洋大学  硕士

2015.09-2019.06  桂林医科大学  学士

代表性论文著作

1.Zhang S, Chen N, Wu F, Xu X, Zheng X, Cheng Z, Wang M, Wu Y, Jiang S, Liu Q, Liu C, Zhang F, Han B. Discovery of therapeutic promising natural products to target Kv1.3 channel, a transmembrane protein regulating immune disorders, through multidimensional virtual screening, molecular dynamics simulations and biological validation. Int J Biol Macromol. 2025 May;308(Pt 2):142636.(SCIIF:8.5, Q1)

2.Zhang S, Liu Y, Javeed A, Jian C, Sun J, Wu S, Han B. Treatment of allergy: Overview of synthetic anti-allergy small molecules in medicinal chemistry. Eur J Med Chem. 2023 Mar 5;249:115151.(SCIIF:7.088, Q1)

3.Zhang SS, Tan QW, Guan LP. Antioxidant, Anti-inflammatory, Antibacterial, and Analgesic Activities and Mechanisms of Quinolines, Indoles and Related Derivatives. Mini Rev Med Chem. 2021;21(16):2261-2275.(SCIIF:3.862, Q2)

4.Li-Ya He¹,Shan-Shan Zhang¹, Ding-Xin Peng, et al., Synthesis and evaluations of selective COX-2 inhibitory effects: Benzo[d]thiazol analogs. Bioorg Med Chem Lett. 2020 Sep 1;30(17):127376. Bioorganic Medicinal Chemistry Letters, 2020, 30, 127376.(SCIIF:2.823, Q2)

5.Shan-Shan Zhang, Wei-Hua Liu, Zhi-Wen He, et al., Synthesis of Chromen-1-phenylpropan-1-one Derivatives and their Anti-depressant/Anticonvulsant Activities Letters in Drug Design Discovery, 2021, 18, 1136-1145.

6.Chen N,Zhang S, Javeed A, Jian C, Liu Y, Sun J, Wu S, Fu P, Han B. Structures and Anti-Allergic Activities of Natural Products from Marine Organisms. Mar Drugs. 2023 Feb 25;21(3):152.(SCIIF:6.085, Q1)

7.Jin QH¹, Zhang LP,Zhang SS¹, et al., (S)-N-Benzyl-1-phenyl-3,4-dihydroisoqunoline-2(1H)carboxamide Derivatives, Multi-Target Inhibitors of Monoamine Oxidase and Cholinesterase: Design, Synthesis, and Biological Activity, Molecules. 2023,9;28(4):1654.(SCIIF:4.927, Q2)

8.Sha Y, Tian Y, Bhutta NK,Zhang S, Xu X, Ren C, Han B. Natural Products for Regulation of Autoimmune Diseases: Chemical Diversity, Pharmacology, and Therapeutic Applications. Chem Biodivers. 2025;22(12):e02362.8

授权发明专利

陈思源等，张珊珊,关丽萍. (2021).一种抗抑郁活性物质BHC-one及其制备与应用. CN113845474A.